Thermo Fisher Scientific ABH1 Polyclonal Antibody
Human ABH1 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB 및 IHC(P)에서 검증됨. 항원 친화 크로마토그래피로 정제되었으며, 0.3 mg/mL 농도의 액상 형태로 제공. DNA 손상 복구 연구용으로 적합하며, 장기 보관 시 -20°C에서 안정적.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
- Publications: References
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
- Publications: References
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ABH1. Recombinant protein control fragment (Product #RP-98356) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2637544 |
Product Specific Information
- Immunogen sequence:
SMVEPCSLED WQVCASYLKT ARVNMTVRQV LATDQNFPLE PIEDEKRDIS TEGFCHLDDQ NSEVKRARIN - Antigen sequence identity:
- Mouse: 74%
- Rat: 74%
Target Information
This gene encodes a homolog to the E. coli alkB gene product. The E. coli alkB protein is part of the adaptive response mechanism of DNA alkylation damage repair. It reverses damage by oxidative demethylation of 1-methyladenine and 3-methylcytosine.
Dioxygenase that repairs alkylated single-stranded DNA and RNA containing 3-methylcytosine by oxidative demethylation. Requires molecular oxygen, alpha-ketoglutarate, and iron.
May play a role in placental trophoblast lineage differentiation.
Has DNA lyase activity and introduces double-stranded breaks at abasic sites. Cleaves both single- and double-stranded DNA at abasic sites, with greatest activity toward double-stranded DNA with two abasic sites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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