Thermo Fisher Scientific CST2 Monoclonal Antibody (OTI5G8), TrueMAB

Applications

• Western Blot (WB)
  • Tested Dilution: 1:1,000

Product Specifications

Target Information

The cystatin superfamily is a well-established family of cysteine protease inhibitors.
Cystatins A and B (type 1) are mainly intracellular; cystatins C, D, E/M, F, G, S, SN, and SA are extracellular (type 2); and the kininogens are type 3 cystatins which are intravascular proteins.
All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, and some also inhibit legumain family enzymes.
Cystatin SA, cystatin S, and cystatin SN are found primarily in saliva, while cystatin S and SN can also be expressed in tears, urine, and seminal fluid.
Cystatin C is expressed in brain, thymus, ovary, epididymis, and vas deferens.
Cystatin D protects against proteinases in the oral cavity, and cystatin E/M and F moderate inhibition of cathepsin proteins.
Fetuins, part of the cystatin superfamily, are secretable proteins that influence osteogenesis, bone resorption, regulation of insulin and hepatocyte growth factor receptors, and systemic inflammation response.
High and low molecular weight kininogens inhibit thrombin- and plasmin-induced aggregation of thrombocytes.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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