Thermo Fisher Scientific NEBL Polyclonal Antibody
인간 NEBL 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50-1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보존. 심근 단백질 연구용으로 적합.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NEBL (Product # RP-90702) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C (short term). For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2644583 |
Product Specific Information
Immunogen sequence:
CTELISDIRY KEEFKKSKDK CTFVTDSPML NHVKNIGAFI SEAKYKGTIK ADLSNSLYKR MPATIDSVFA GEVTQLQSEV AYKQKHDAAK GFSDYAHMKE PPEVKHAMEV NKHQSNISYR KDVQDTHTYS AELDRPD
Highest antigen sequence identity to the following orthologs:
- Mouse: 88%
- Rat: 85%
Target Information
Nebulette encodes a nebulin-like protein abundantly expressed in cardiac muscle. The encoded protein binds actin and interacts with thin filaments and Z-line associated proteins in striated muscle. It may play a role in cardiac myofibril assembly.
A shorter isoform, termed LIM nebulette, is expressed in non-muscle cells and may function as a component of focal adhesion complexes.
Alternate splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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