Thermo Fisher Scientific Macro H2A.2 Monoclonal Antibody (OTI1F5)
인간 H2AFY2 단백질(aa 2-261)을 면역원으로 제작된 마우스 단클론 항체. Western blot과 IHC(P)에서 검증됨. 1 mg/mL 액상형, PBS/BSA/glycerol 완충액에 보관. -20°C에서 보관하며 동결/해동 반복은 피해야 함.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 2–261 of H2AFY2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724626 |
Target Information
Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones (histone code) and nucleosome remodeling. May be involved in stable X chromosome inactivation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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