Thermo Fisher Scientific GRIP1 Polyclonal Antibody
Rabbit polyclonal antibody targeting GRIP1 for human, mouse, and rat samples. Validated for Western blot with high specificity. Supplied as unconjugated liquid form, purified by affinity chromatography. Ideal for research on nuclear receptor coactivators.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthesized peptide derived from human GRIP1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2692230 |
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Steroid and thyroid hormones and retinoic acid regulate gene expression via intracellular receptor transcription factors belonging to the ligand-dependent nuclear receptor superfamily. Coactivators and corepressors modulate transcription activity of these receptors.
Glucocorticoid receptor interacting protein-1 (GRIP1), also known as Transcription Intermediary Factor 2 (TIF2), is a transcriptional coactivator related to SRC-1 and AIB-1.
GRIP1 interacts with and stimulates transcriptional activity of retinoic acid, retinoid X, vitamin D, mineralocorticoid, glucocorticoid, thyroid hormone, androgen, estrogen, progesterone, and peroxisome proliferator activated receptors.
It contains several conserved LXXLL/LLXXL motifs critical for receptor-coactivator interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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