Thermo Fisher Scientific CDCA7L Monoclonal Antibody (OTI3B5)
CDCA7L 단백질을 표적하는 Thermo Fisher Scientific의 단클론 항체입니다. Western blot 및 IHC(파라핀) 실험에 적합하며, 인간 시료 반응성을 갖습니다. 고순도의 액상 항체로 안정적인 신호 검출이 가능합니다. 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–337 of CDCA7L produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724110 |
Target Information
Cell division cycle-associated 7-like protein (CDCA7L, also known as RAM2) is a transcription factor involved in transcriptional regulation and apoptotic signaling pathways.
It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to its promoter.
CDCA7L plays an oncogenic role in mediating the transforming effect of MYC in medulloblastoma cells, and may function downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3, CCND1/cyclin D1, and E2F1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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