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Thermo Fisher Scientific CD11b Monoclonal Antibody (ICRF44), Brilliant Violet 650, eBioscience
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Thermo Fisher Scientific

Thermo Fisher Scientific CD11b Monoclonal Antibody (ICRF44), Brilliant Violet 650, eBioscience

상품 한눈에 보기

인간 CD11b 인테그린을 검출하는 ICRF44 단클론 항체로, Brilliant Violet 650 형광체가 결합되어 있습니다. 유세포 분석에 최적화되어 있으며, 다양한 영장류에 반응합니다. 광민감성이 있어 암실 보관이 필요하며, 메탄올 고정에는 부적합합니다.

카탈로그번호
416-0118-4x (2개 옵션)
브랜드
Thermo Fisher Scientific
카테고리
Monoclonal Antibodies
판매단위
pk

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2개 옵션
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마지막 업데이트 2025. 08. 05. 오후 02:31
Thermo Fisher Scientific 416-0118-42 CD11b Monoclonal Antibody (ICRF44), Brilliant Violet 650, eBioscience 100 tests pk판매 단위 pk ·
재고 확인 필요
564,100원VAT 포함 620,510원
Thermo Fisher Scientific 416-0118-41 CD11b Monoclonal Antibody (ICRF44), Brilliant Violet 650, eBioscience 25 tests pk판매 단위 pk ·
재고 확인 필요
240,500원VAT 포함 264,550원
재고문의·견적요청 옵션은 실시간 상담으로 납기를 확인해 드립니다 · 연구비 카드 결제 가능

Thermo Fisher Scientific · Thermo Fisher Scientific CD11b Monoclonal Antibody (ICRF44), Brilliant Violet 650, eBioscience

Thermo Fisher Scientific CD11b Monoclonal Antibody (ICRF44), Brilliant Violet 650, eBioscience™

Applications and Tested Dilution

  • Flow Cytometry (Flow): 5 µL (0.125 µg)/test

Species Reactivity

  • Baboon
  • Chimpanzee
  • Cynomolgus monkey
  • Human
  • Rhesus monkey

Product Specifications

항목 내용
Host / Isotype Mouse / IgG1, kappa
Recommended Isotype Control Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), Brilliant Violet™ 650
Class Monoclonal
Type Antibody
Clone ICRF44
Conjugate Brilliant Violet™ 650
Excitation / Emission Max 407 / 646 nm
Form Liquid
Concentration 5 µL/test
Purification Affinity chromatography
Storage Buffer PBS, pH 7.2, with BSA
Contains 0.09% sodium azide
Storage Conditions 4°C, store in dark, DO NOT FREEZE
Shipping Conditions Ambient (domestic); Wet ice (international)
RRID AB_2925671

Additional Available Formats

  • Unconjugated
  • Alexa Fluor 700
  • APC
  • APC-eFluor 780
  • Biotin
  • Brilliant UV / Brilliant Violet / eFluor / FITC / NovaFluor / PE / Super Bright 시리즈
  • Request custom conjugation

Product Specific Information

The ICRF44 monoclonal antibody reacts with human CD11b, a 165 kDa adhesion molecule. CD11b associates with integrin beta2 (CD18) and is expressed on monocytes, granulocytes, activated lymphocytes, and a subset of NK cells. It serves as a receptor for ICAM family members (CD54, CD102, CD50) and iC3b, playing a key role in cell-cell and cell-matrix interactions.

  • Applications Reported: Flow cytometric analysis
  • Applications Tested: Pre-diluted; use at 5 µL (0.125 µg) per test
  • Brilliant Violet™ 650 (BV650): Emits at 649 nm; use with violet (405 nm) laser
  • Buffer Recommendation: Use Super Bright Complete Staining Buffer (SB-4401-42) or Brilliant Stain Buffer™ (00-4409-75) to minimize polymer interactions
  • Light Sensitivity: Protect from light
  • Fixation: Compatible with IC Fixation Buffer (00-8222-49) or 1-step Fix/Lyse Solution (00-5333-54); not compatible with methanol-based fixation
  • Excitation / Emission / Laser: 407 nm / 649 nm / Violet Laser

BRILLIANT VIOLET™ is a trademark or registered trademark of Becton, Dickinson and Company or its affiliates, and is used under license. Powered by Sirigen™.

Target Information

CD11b (integrin alpha-M, ITGAM) forms a heterodimer with CD18 (integrin beta-2) known as Mac-1 or CR3. It is expressed on monocytes/macrophages, granulocytes, activated lymphocytes, NK cells, dendritic cells, and microglia. CD11b/CD18 acts as a receptor for ICAMs, CD14, fibrinogen, and Factor X, mediating key adhesion and immune interactions. Expression varies by cell type and tissue, and is used as a microglial marker. Dysfunction is associated with systemic lupus erythematosus and ITGAM-related susceptibility.

For Research Use Only. Not for use in diagnostic procedures.

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