Thermo Fisher Scientific Phospho-HMGN1 (Ser21, Ser25) Polyclonal Antibody
HMGN1 단백질의 Ser21 및 Ser25 인산화 부위를 특이적으로 인식하는 Rabbit Polyclonal 항체. WB, IHC, ICC, ELISA 등 다양한 응용에 적합. Human, Mouse, Rat 반응성. 고순도 Protein A 정제, 안정적인 액상 형태로 제공.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic phosphopeptide derived from human HMGN1 around the phosphorylation site of Ser20+Ser24 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
High-mobility group (HMG) proteins 14 and 17 are abundant chromosomal proteins that bind to nucleosomes and enhance transcription. These proteins act as architectural elements, altering chromatin structure and facilitating transcription from chromatin templates.
HMG-14/17 proteins modify the nucleosomal organization of the 30 nm chromatin fiber and mediate unfolding of higher-order chromatin structures, enhancing DNA accessibility.
They are also constitutive components of mouse oocyte and embryonic chromatin, linking chromatin structure to embryonic development progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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