Thermo Fisher Scientific IMP3 Polyclonal Antibody
Rabbit에서 생산된 폴리클로날 IMP3 항체로 Western blot 및 Immunoprecipitation에 적합. 인간 IGF2BP3 단백질의 529-579번 잔기 영역을 면역원으로 사용. 액상 형태, 0.20 mg/mL 농도, 4°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- A303426Ax (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific IMP3 Polyclonal Antibody
Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 529 and 579 of human Insulin-Like Growth Factor 2 mRNA Binding Protein 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Insulin-like growth factor-II messenger RNA (mRNA)-binding protein-3 (IMP-3), also known as K homology domain-containing protein overexpressed in cancer (KOC) and L523S, is a member of the insulin-like growth factor-II mRNA-binding protein family.
IMP-3 is expressed during embryogenesis and in some malignancies. It is found in malignant melanoma but not in benign nevi, even when dysplastic features are present. IMP-3 expression is significantly higher in melanomas than in Spitz nevi and in metastatic melanomas compared to thin melanomas.
IMP-3 appears to be involved in the progression of malignant melanoma and may play an important role in regulating the biological behavior of this tumor.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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