Thermo Fisher Scientific ADAMTS2 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ADAMTS2, validated for IHC and IHC (Paraffin) applications. Detects endogenous ADAMTS2 protein. High purity via antigen affinity chromatography. Supplied in PBS with 40% glycerol, suitable for research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:25–1:100 | View publication |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues near the C-terminal of human ADAM metallopeptidase with thrombospondin type 1 motif, 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.8 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2635992 |
Product Specific Information
The antibody detects endogenous levels of total ADAMTS2 protein.
Target Information
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members differ in the number of C-terminal TS motifs, and some have unique C-terminal domains.
The enzyme encoded by this gene excises the N-propeptide of type I, type II, and type V procollagens. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in two transcript variants, with the short transcript encoding a protein lacking significant procollagen N-peptidase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지 파일명: PA5-50539_ADAMTS2_O95450-1_Rabbit.svg, PA5-50539_ADAMTS2_O95450-1_Rabbit_PDP.jpeg)
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