Thermo Fisher Scientific MAST2 Polyclonal Antibody
MAST2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB 및 ICC/IF에 사용 가능하며, Human, Mouse, Rat 반응성 확인. 고순도 항원 친화 크로마토그래피 정제, 1 mg/mL 농도, PBS/glycerol 저장.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: Not specified
- Publication: 1 available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 1205–1249 of Human MAST2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C (avoid freeze/thaw cycles). |
| Shipping Conditions | Wet ice |
| RRID | AB_2719702 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. Purity >95% (by SDS-PAGE).
Target Information
Syntrophin is an adapter protein that binds signaling molecules to the dystrophin-associated protein complex, linking the extracellular matrix to the intracellular cytoskeleton.
Microtubule-associated serine/threonine-protein kinase 2 (MAST205) is a testis-specific cytoplasmic protein involved in spermatid maturation and interaction with the dystrophin/utrophin network via Syntrophin.
MAST205 regulates IL-12 synthesis in macrophages by forming a complex with TRAF6, inhibiting TRAF6 NF-kappa-B activation.
Two isoforms exist due to alternative splicing: Isoform 1 (full length) and Isoform 2 (lacking residues 327–396 and 1091–1113).
Phosphorylation at the N-terminus enables ubiquitination and subsequent proteasome-mediated degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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