Thermo Fisher Scientific Human MAP3K14 (NIK), GST Tag Recombinant Protein

Thermo Fisher Scientific Human MAP3K14 (NIK), GST Tag Recombinant Protein

Applications

• Kinase Assay (KA)

Tested Dilution

• Assay-dependent

Product Specifications

Product Specific Information

• For maximum recovery, please spin prior to use.
• Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use in original packaging until exhausted.
• For larger sizes, aliquoting can reduce freeze/thaw cycles; aliquots below 20 µL are not recommended.
• Never store kinase diluted.
• Properly stored at -80°C, product is guaranteed for 6 months from date of purchase.
• Protein Form: Recombinant, Catalytic

Target Information

MAP3K14 (NIK) is structurally related to MAP3Ks. It phosphorylates and activates CHUK (IKKα) and IKBKB (IKKβ), which in turn phosphorylate IκB-α, releasing NF-κB and upregulating inflammatory response genes.
This kinase binds to TRAF2 and stimulates NF-κB activity. It shares sequence similarity with several other MAPKK kinases and participates in an NF-κB-inducing signaling cascade common to TNF/NGF family receptors and the interleukin-1 type-I receptor.

Usage Notice

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.