Thermo Fisher Scientific SOX8 Polyclonal Antibody
Rabbit polyclonal antibody against human SOX8. Validated for ICC/IF applications. Antigen affinity purified and supplied in PBS with glycerol. Suitable for research use only, not for diagnostic or resale.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human SOX8. Recombinant protein control fragment (Product #RP-106880) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663016 |
Product Specific Information
Immunogen sequence:
PRRRKSAKAGH SDSDSGAELG PHPGGGAVYK AEAGLGDGHH HGDHTGQTH
Highest antigen sequence identity to the following orthologs:
- Mouse: 73%
- Rat: 70%
Target Information
Sox genes comprise a family of genes related to the mammalian sex-determining gene SRY. These genes contain sequences encoding the HMG-box domain, responsible for sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in cell fate decisions during development and in the control of various developmental processes.
The Sox gene family is complex, consisting of at least 40 different loci that have diverged across animal lineages. Approximately 30 Sox genes have been identified to date, conserved through evolution and playing key roles in animal development. Some Sox genes are involved in human diseases, including sex reversal.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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