Thermo Fisher Scientific SCD Monoclonal Antibody (CD.E10)
SCD1 단백질을 표적으로 하는 Thermo Fisher Scientific의 CD.E10 단클론 항체. Western Blot, IHC, ICC/IF, ELISA, IP 등 다양한 응용 가능. 인간, 생쥐, 랫트 반응성. Protein A 정제, 액상 형태, -20°C 보관.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | - | View 1 publication |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | - | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:100–1:1,000 | View 1 publication |
| ELISA | Assay-Dependent | - |
| Immunoprecipitation (IP) | Assay-Dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | CD.E10 |
| Immunogen | Full length human recombinant protein against SCD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723611 |
Target Information
Stearoyl-CoA desaturase (SCD; EC 1.14.99.5) is an iron-containing enzyme that catalyzes a rate-limiting step in the synthesis of unsaturated fatty acids. The principal product of SCD is oleic acid, formed by desaturation of stearic acid. The ratio of stearic to oleic acid influences cell growth and differentiation through membrane fluidity and signal transduction.
Four SCD isoforms (Scd1–Scd4) exist in mouse, while humans have two (SCD1 and SCD5). SCD1 shares ~85% amino acid identity with mouse and rat isoforms, whereas SCD5 is unique to primates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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