Thermo Fisher Scientific F11R Monoclonal Antibody (OTI3H3), TrueMAB
Human F11R(JAM-A/CD321) 단백질을 표적으로 하는 마우스 모노클로날 항체로, WB, IHC, ICC/IF에 사용 가능. 고순도 친화 크로마토그래피 정제, 액상 형태, PBS/BSA/glycerol 버퍼 포함. 연구용으로 세포 접착 및 막 단백질 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H3 |
| Immunogen | Full length human recombinant protein of human F11R produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD321 (F11R, JAM-1, JAM-A) is a cell-surface adhesion molecule belonging to the Ig superfamily of receptors. It is a 32–41 kDa glycoprotein with two extracellular Ig-like domains, a transmembrane region, and a short cytosolic tail.
The protein forms homodimers and interacts with other membrane proteins including integrins. CD321 is expressed on leukocytes, platelets, erythrocytes, stem cells, epithelial and endothelial cells, and plays a key role in mediating cell-cell contact.
It is associated with epithelial tight junction components such as ZO-1 and occludin, contributing to epithelial and endothelial barrier maintenance, hematopoiesis, angiogenesis, and tumor proliferation, invasion, and metastasis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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