Thermo Fisher Scientific Human ABL2 (Arg), His Tag Recombinant Protein

Applications

• Kinase Assay (KA): Assay-dependent

Product Specifications

Product Specific Information

For maximum recovery, please spin prior to use.
Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended; use materials in original packaging until exhausted.
For larger sizes, aliquoting can reduce freeze/thaw cycles. Aliquots below 20 µL are not recommended.
Do not store kinase diluted.
If properly stored at -80°C, this product is guaranteed for 6 months from date of purchase.

Protein Form: Recombinant, Full Length

Target Information

ABL2 (Arg) is an Abl-related non-receptor protein tyrosine kinase that links cell surface receptors to cell proliferation and cytoskeletal reorganization.
It encodes a member of the Abelson family of nonreceptor tyrosine protein kinases, highly similar to ABL1, containing tyrosine kinase, SH2, and SH3 domains.
ABL2 plays a role in cytoskeletal rearrangements via its C-terminal F-actin and microtubule-binding sequences.
Expressed in both normal and tumor cells, ABL2 is involved in translocation with the ETV6 gene in leukemia.
Multiple alternatively spliced transcript variants encoding different isoforms have been identified.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.