Thermo Fisher Scientific FGFR1 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1366)
FGFR1 단백질을 인식하는 알파카 유래 재조합 단일클론 항체. Western blot, ICC/IF, ELISA, SPR 등 다양한 분석에 사용 가능. CHO 세포 발현, Metal-chelate chromatography 정제. PBS 용액 형태, 보존제 없음. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunocytochemistry (ICC/IF)
- Tested Dilution: Assay-dependent
ELISA
- Tested Dilution: Assay-dependent
Surface Plasmon Resonance (SPR)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1366 |
| Immunogen | Recombinant Human CD331/FGFR1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
FGFR1 (also known as FLT2) is a member of the Fibroblast Growth Factor Receptor (FGFR) family, which includes four membrane-spanning tyrosine kinases (FGFR1–4). These receptors serve as high-affinity receptors for 17 fibroblast growth factors (FGF1–17). The FGFR family is involved in key biological processes such as mesoderm induction, cell growth, migration, organ formation, and bone development.
FGFR1 undergoes alternative splicing, producing multiple isoforms that are differentially expressed during embryogenesis and in adult tissues. Mutations or aberrations in FGFR1 are linked to several disorders, including Pfeiffer syndrome, idiopathic hypogonadotropic hypogonadism, Kallmann syndrome type 2, osteoglophonic dysplasia, non-syndromic trigonocephaly, Jackson-Weiss syndrome, and Antley-Bixler syndrome. Chromosomal abnormalities involving FGFR1 are also associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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