Thermo Fisher Scientific SRSF2 Polyclonal Antibody
SRSF2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC/IF 실험에 적합합니다. 인간, 생쥐, 랫드 반응성을 가지며 고순도 Affinity chromatography로 정제되었습니다. PBS 및 50% glycerol buffer에 보관되며 -20°C에서 저장합니다.
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Thermo Fisher Scientific SRSF2 Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human SRSF2 (Accession Q01130), corresponding to amino acid residues D73–R123 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900502 |
Product Specific Information
Antibody detects endogenous levels of total SC35.
Target Information
The protein encoded by SC35 is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome.
Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins.
The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors.
In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation.
Two transcript variants encoding the same protein and one non-coding transcript variant have been found for SC35.
In addition, a pseudogene of SC35 has been found on chromosome 11.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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