Thermo Fisher Scientific TCR DO11.10 Monoclonal Antibody (KJ126.1)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

5 µg/mL

-

ELISA (ELISA)

Assay-dependent

View 1 publication 1 publication

Product Specifications

Species Reactivity

Mouse

Published species

Not Applicable

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

KJ126.1

Immunogen

DO-11.10 T cell hybridoma

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Protein A

Storage buffer

PBS

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2539419

Product Specific Information

This antibody is specific for the DO-11.10 T cell receptor idiotype. The DO-11.10 TCR is specific for chicken ovalbumin (aa 323-339) in combination with I-Ad MHC class II complex. KJ1-26 has been reported to block the antigen response of the DO-11.10 T cell hybridomas in vitro.

Target Information

TCR DO11 (DO11.10) is a receptor found on lymphocytes of DO11.10 transgenic mice and T-cell receptors of BALB/c-derived DO11.10 and DO11.10.24 T cell hybridomas. The DO11.10 TCR recognizes a C-terminal ovalbumin peptide (OVA 323-339) in the context of I-Ad major histocompatibility molecules. The use of antibodies against DO11.10 have proven to be instrumental in describing many of the intricate details of T cell immunity, including T cell activation, development, and function.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.