ELK Biotechnology CD85c rabbit pAb
CD85c 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA 등에 사용 가능. 인간, 쥐, 랫트에 반응하며 세포막 단백질 연구에 적합. 고순도 IgG 형태로 -20°C에서 1년 보관 가능.
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CD85c rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CD85c rabbit pAb |
| Alternative Names | LILRB5; LIR8; Leukocyte immunoglobulin-like receptor subfamily B member 5; CD85 antigen-like family member C; Leukocyte immunoglobulin-like receptor 8; LIR-8; CD85c |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 IHC-p: 1/100–1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from the N-terminal region of human LILRB5 (AA range: 21–70) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 65 kDa |
| Gene ID (Human) | 10990 |
| Human Swiss-Prot No. | O75023 |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Rat; Mouse |
Background
This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is located in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors that contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. (RefSeq, Jul 2008)
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