ELK Biotechnology EF-1 α1/2 rabbit pAb
EF-1 α1/2 단백질을 인식하는 토끼 폴리클로날 항체로, Western blot과 ELISA에 적합합니다. 인간, 마우스, 랫트 시료에서 반응하며 세포질과 핵에 위치합니다. 고순도 IgG 형식으로 -20°C에서 1년 보관 가능합니다.
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제품명
EF-1 α1/2 rabbit pAb
제품 개요
EF-1 α1/2 단백질을 인식하는 토끼 유래 폴리클로날 항체입니다. 단백질 합성과 관련된 EF-1 복합체의 알파 서브유닛을 표적하며, 다양한 조직에서 발현됩니다. Western blot 및 ELISA 분석에 적합합니다.
상세 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | EEF1A1; EEF1A; EF1A; LENG7; Elongation factor 1-alpha 1; EF-1-alpha-1; Elongation factor Tu; EF-Tu; Eukaryotic elongation factor 1 A-1; eEF1A-1; Leukocyte receptor cluster member 7; EEF1A2; EEF1AL; STN; Elongation factor 1-alpha 2; EF-1-alpha-2; Eukaryotic elongation factor 1 A-2; eEF1A-2; Statin-S1; EEF1A1P5; EEF1AL3; Putative elongation factor 1-alpha-like 3; EF-1-alpha-like 3; Eukaryotic elongation factor 1 A-like 3; eEF1A-like 3; Eukaryotic translation elongation factor 1 alpha-1 pseudogene 5 |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the N-terminal region of human EF-1 α1/2 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 50 kD |
| Gene ID (Human) | 1915 / 1917 |
| Human Swiss-Prot No | P68104 / Q05639 / Q5VTE0 |
| Species Reactivity | Human; Mouse; Rat |
| Storage | -20°C / 1 year |
세포 내 위치
Cytoplasm, Nucleus, Nucleolus, Cell membrane.
Colocalizes with DLC1 at actin-rich regions in the cell periphery (PubMed:19158340).
Translocates with ZPR1 from cytoplasm to nucleus and nucleolus after mitogen treatment (PubMed:8650580).
Localization at the cell membrane depends on EEF1A1 phosphorylation status and PPP1R16B presence (PubMed:26497934).
배경 정보
This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome.
Isoform alpha 1 is expressed in brain, placenta, lung, liver, kidney, and pancreas, while alpha 2 is expressed in brain, heart, and skeletal muscle.
This isoform is identified as an autoantigen in 66% of patients with Felty syndrome.
Multiple copies exist on many chromosomes, some representing different pseudogenes.
(RefSeq, Jul 2008)
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