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ELK Biotechnology FMO3 rabbit pAb
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ELK Biotechnology FMO3 rabbit pAb

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FMO3 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA에 사용 가능. 인간, 랫드, 마우스에 반응하며, 간에서 발현되는 약물 대사 효소 연구에 적합. -20°C에서 1년 보관 가능.

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ELK Biotechnology ES4183-100UL FMO3 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES4183-50UL FMO3 rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology FMO3 rabbit pAb

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FMO3 rabbit pAb

제품 정보

항목 내용
Alternative Names FMO3; Dimethylaniline monooxygenase [N-oxide-forming] 3; Dimethylaniline oxidase 3; FMO II; FMO form 2; Hepatic flavin-containing monooxygenase 3; FMO 3; Trimethylamine monooxygenase
Applications WB; IHC; IF; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
IHC-p: 1/100 - 1/300
ELISA: 1/20000
Not yet tested in other applications
Immunogen The antiserum was produced against synthesized peptide derived from the internal region of human FMO3 (AA range: 101–150)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 58 kDa
Gene ID (Human) 2328
Human Swiss-Prot No. P31513
Cellular Localization Microsome membrane; Single-pass membrane protein; Endoplasmic reticulum membrane; Single-pass membrane protein
Species Reactivity Human; Rat; Mouse

Background

Flavin-containing monooxygenase 3 (FMO3) is a key enzyme in the metabolism of xenobiotics, catalyzing NADPH-dependent oxygenation of nitrogen-, sulfur-, and phosphorus-containing compounds such as drugs, dietary substances, and pesticides. The human FMO gene family comprises five genes and multiple pseudogenes, with distinct developmental and tissue-specific expression patterns. FMO3, the major isoform expressed in adult liver, shows up to 20-fold variation among individuals, influencing the rate of xenobiotic metabolism. This transmembrane protein localizes to the endoplasmic reticulum of many tissues, and alternative splicing of this gene has been observed.

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