ELK Biotechnology SERCA2 rabbit pAb
SERCA2 rabbit pAb는 인간, 생쥐, 랫드, 닭 시료에 반응하는 다클론 항체입니다. WB, IHC, IF, ELISA 등에 사용 가능하며, ATP2A2 단백질의 C-말단 펩타이드로부터 제작되었습니다. 근육세포 내 Ca2+ 펌프 연구에 적합합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology SERCA2 rabbit pAb
제품명
SERCA2 rabbit pAb
공급업체
ELK Biotechnology
제품 개요
SERCA2 rabbit pAb는 Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2 (ATP2A2)를 인식하는 다클론 항체입니다. 근육세포 내 칼슘 이동과 수축/이완 조절 연구에 활용됩니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | ATP2A2; ATP2B; Sarcoplasmic/endoplasmic reticulum calcium ATPase 2; SERCA2; SR Ca(2+)-ATPase 2; Calcium pump 2; Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletal muscle isoform; Endoplasmic reticulum class 1/2 Ca(2+) ATPase |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 IHC-p: 1/100–1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the C-terminal region of human ATP2A2 (AA range: 841–890) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 115 kDa |
| GeneID (Human) | 488 |
| Human Swiss-Prot No | P16615 |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein. |
| Species Reactivity | Human; Mouse; Rat; Chicken |
Background
This gene encodes one of the SERCA Ca(2+)-ATPases, intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. The enzyme catalyzes ATP hydrolysis coupled with calcium translocation from the cytosol into the sarcoplasmic reticulum lumen, regulating the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease (keratosis follicularis), an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Alternative splicing results in multiple transcript variants encoding different isoforms. [RefSeq, Oct 2008]
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.