ELK Biotechnology HSP70 rabbit pAb
HSP70 rabbit pAb는 인간, 생쥐, 랫트에서 반응하는 폴리클로날 항체로, IF, WB, IHC, ELISA에 사용 가능. 세포 스트레스 반응 관련 단백질 검출에 적합하며, 70kDa 밴드를 인식. 고순도 IgG 형식으로 안정적 저장 가능.
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ELK Biotechnology HSP70 rabbit pAb
제품 개요
HSP70 rabbit pAb는 Heat Shock Protein 70(HSP70)에 특이적인 폴리클로날 항체로, 세포 스트레스 반응 및 단백질 폴딩 연구에 활용됩니다. 인간, 생쥐, 랫트 시료에서 반응하며, 다양한 면역분석 응용에 적합합니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Product name | HSP70 rabbit pAb |
| Alternative Names | HSPA1A; HSPA1; HSPA1B; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2 |
| Applications | IF; WB; IHC; ELISA |
| Recommended Dilutions | IF: 1:50–200; WB: 1:500–1:2000; IHC-p: 1:100–1:300; ELISA: 1:20000 (Other applications not yet tested) |
| Immunogen | Synthesized peptide derived from human HSP70 around the non-acetylation site of K246 |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 70 kD |
| GeneID (Human) | 3303 / 3304 |
| Human Swiss-Prot No | P0DMV8 / P0DMV9 |
| Cellular Localization | Cytoplasm; Nucleus; Cytoplasm, cytoskeleton, microtubule organizing center, centrosome; Secreted; Localized in cytoplasmic mRNP granules containing untranslated mRNAs |
| Storage | -20°C / 1 year |
| Host | Rabbit |
Background
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
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