ELK Biotechnology CD148 rabbit pAb
CD148 단백질을 인식하는 토끼 다클론 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간 PTPRJ 내부 서열 유래 펩타이드로 면역화되었으며, 세포막 및 세포 접합부에 위치한 단백질 검출에 활용됩니다. 1 mg/ml 농도, -20°C에서 1년 보관 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology CD148 rabbit pAb
CD148 rabbit pAb
제품 개요
CD148 단백질을 인식하는 토끼 다클론 항체로, 다양한 면역학적 분석(WB, IHC, IF, ELISA)에 사용됩니다. 인간 PTPRJ 내부 영역(AA 861–910) 유래 합성 펩타이드로 면역화되었습니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | CD148 rabbit pAb |
| Alternative Names | PTPRJ; DEP1; Receptor-type tyrosine-protein phosphatase eta; Protein-tyrosine phosphatase eta; R-PTP-eta; Density-enhanced phosphatase 1; DEP-1; HPTP eta; Protein-tyrosine phosphatase receptor type J; R-PTP-J; CD148 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000; IHC-p: 1/100–1/300; ELISA: 1/20000 (other applications not yet tested) |
| Immunogen | Synthesized peptide derived from the internal region of human PTPRJ (AA range: 861–910) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 150 kDa |
| Gene ID (Human) | 5795 |
| Human Swiss-Prot No | Q12913 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein; Cell projection (ruffle membrane); Cell junction. After T-cell stimulation, temporarily excluded from immunological synapses. |
| Species Reactivity | Human; Rat; Mouse |
Background
The protein encoded by the PTPRJ gene belongs to the protein tyrosine phosphatase (PTP) family, which regulates various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This receptor-type PTP contains five fibronectin type III repeats, a transmembrane region, and a cytoplasmic catalytic domain.
It is expressed in all hematopoietic lineages and negatively regulates T cell receptor signaling, possibly by interfering with phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells.
Additionally, it can dephosphorylate the PDGF beta receptor and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been identified.
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.