ELK Biotechnology ALPP/ALPPL2 rabbit pAb
인간 및 생쥐 시료에 반응하는 ALPP/ALPPL2 rabbit polyclonal antibody로, Western blot과 ELISA에 적합합니다. 합성 펩타이드 항원으로 제작되었으며, 세포막 GPI-anchor 단백질 검출에 활용됩니다. 고순도 IgG, 1 mg/ml 농도, -20°C에서 1년 보관 가능합니다.
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제품명
ALPP/ALPPL2 rabbit pAb
기본 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | ALPP; PLAP; Alkaline phosphatase, placental type; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; PLAP-1; ALPPL2; ALPPL; Alkaline phosphatase, placental-like ALP-1; Alkaline phosphatase Nagao isozyme; Germ cell alkaline phosphatase; GCAP; Placental alkaline phosphatase-like; PLAP-like |
| Applications | WB; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the N-terminal region of human ALPP/ALPPL2 (AA range: 1–50) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 60 kD |
| GeneID (Human) | 250 / 251 |
| Human Swiss-Prot No | P05187 / P10696 |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor |
| Species Reactivity | Human; Mouse |
Background
The protein encoded by this gene is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and endometrial tissue; however, strong ectopic expression has been detected in ovarian adenocarcinoma, serous cystadenocarcinoma, and other ovarian cancer cells.
[provided by RefSeq, Jan 2015]
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