ELK Biotechnology L-Selectin rabbit pAb
L-Selectin rabbit pAb는 인간, 마우스, 랫트에서 반응하는 다클론 항체로, WB, ELISA, IHC에 사용됩니다. 세포막 단백질 L-Selectin을 표적하며 염증 및 림프구 이동 연구에 적합합니다. 고순도 IgG 형태로 -20°C에서 1년간 안정적으로 보관 가능합니다.
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제품명
L-Selectin rabbit pAb
대체 명칭
SELL; LNHR; LYAM1; L-selectin; CD62 antigen-like family member L; Leukocyte adhesion molecule 1; LAM-1; Leukocyte surface antigen Leu-8; Leukocyte-endothelial cell adhesion molecule 1; LECAM1; Lymph node homing receptor; TQ1; gp90-MEL; CD62L
적용 분야
- WB
- ELISA
- IHC
권장 희석 배율
- WB: 1:500–2000
- IHC-p: 1:50–300
- ELISA: 1:2000–20000
면역원
The antiserum was produced against synthesized peptide derived from the internal region of human SELL (AA range: 91–140).
보관 및 안정성
- 종: Rabbit
- 보관 조건: -20°C / 1년
항체 특성
| 항목 | 내용 |
|---|---|
| Clonality | Polyclonal |
| Isotype | IgG |
| 농도 | 1 mg/ml |
| Observed Band | 42 kD |
| GeneID (Human) | 6402 |
| Swiss-Prot No. (Human) | P14151 |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Species Reactivity | Human; Mouse; Rat |
배경 정보
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leukocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]
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