ELK Biotechnology NTE rabbit pAb
NTE rabbit pAb는 인간 PNPLA6 단백질을 인식하는 다클론 항체로, WB, IHC, IF, ELISA에 사용 가능. 내인성 신경 관련 단백질 연구에 적합하며, 고순도 IgG 형태로 제공. -20°C에서 1년 보관 가능.
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ELK Biotechnology NTE rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | NTE rabbit pAb |
| Alternative Names | PNPLA6; NTE; Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 IHC-p: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from the internal region of human PNPLA6 (AA range: 1031–1080) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 150 kDa |
| GeneID (Human) | 10908 |
| Human Swiss-Prot No | Q8IY17 |
| Cellular Localization | Endoplasmic reticulum membrane; Single-pass type III membrane protein |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. (RefSeq, Oct 2009)
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