ELK Biotechnology Arg rabbit pAb
Arg rabbit pAb는 ABL2 단백질을 인식하는 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. 인간, 생쥐, 랫트 시료에 반응하며, 세포 골격 관련 단백질 연구에 유용합니다. -20°C에서 1년 보관 가능합니다.
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제품명
Arg rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | ABL2; ABLL; ARG; Abelson tyrosine-protein kinase 2; Abelson murine leukemia viral oncogene homolog 2; Abelson-related gene protein; Tyrosine-protein kinase ARG |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500 - 1/2000 IHC-p: 1/100 - 1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | The antiserum was produced against synthesized peptide derived from the internal region of human ABL2 (AA range: 601–650) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 130 kD |
| GeneID (Human) | 27 |
| Human Swiss-Prot No | P42684 |
| Cellular Localization | Cytoplasm, cytoskeleton |
| Species Reactivity | Human; Mouse; Rat |
Background
This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
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