ELK Biotechnology Cytokeratin 19 rabbit pAb
Cytokeratin 19 단백질을 인식하는 rabbit polyclonal antibody로, WB, IHC, IF, ELISA에 사용 가능. 인간, 생쥐, 랫트 반응성. 고순도 IgG 형태로 -20°C에서 1년 보관 가능. 세포 구조 연구 및 표지에 적합.
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Cytokeratin 19 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | Cytokeratin 19 rabbit pAb |
| Alternative Names | KRT19; Keratin, type I cytoskeletal 19; Cytokeratin-19; CK-19; Keratin-19; K19 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC-p: 1/100–1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the C-terminal region of human KRT19 (AA range: 321–370) |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 44 kD |
| Gene ID (Human) | 3880 |
| Human Swiss-Prot No | P08727 |
| Cellular Localization | Intermediate filament, plasma membrane, dystrophin-associated glycoprotein complex, Z disc, sarcolemma, costamere, extracellular exosome, cell periphery, terminal web |
| Species Reactivity | Human, Rat, Mouse |
Background
The protein encoded by this gene is a member of the keratin family. Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Type I cytokeratins consist of acidic proteins arranged in pairs of heterotypic keratin chains. Unlike related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transient superficial layer enveloping the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12–q21 (provided by RefSeq, Jul 2008).
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