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ELK Biotechnology EPAS-1 rabbit pAb
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EPAS-1 단백질을 인식하는 토끼 폴리클로날 항체로, IF, WB, IHC, ELISA 등에 사용 가능. 인간, 마우스, 랫트에 반응하며 핵에서 발현되는 HIF-2α 관련 연구에 적합. 고순도 IgG, 1 mg/ml 농도로 제공.
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ELK Biotechnology ES4055-100UL EPAS-1 rabbit pAb, 100UL pk판매 단위 pk ·
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ELK Biotechnology ES4055-50UL EPAS-1 rabbit pAb, 50UL pk판매 단위 pk ·
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ELK Biotechnology · ELK Biotechnology EPAS-1 rabbit pAb
제품명
EPAS-1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | EPAS1; BHLHE73; HIF2A; MOP2; PASD2; Endothelial PAS domain-containing protein 1; EPAS-1; Basic-helix-loop-helix-PAS protein MOP2; Class E basic helix-loop-helix protein 73; bHLHe73; HIF-1-alpha-like factor; HLF; Hypoxia-inducible factor 2-alpha; HIF-2-alpha; HIF2-alpha; Member of PAS protein 2; PAS domain-containing protein 2 |
| Applications | IF; WB; IHC; ELISA |
| Recommended Dilutions | IF: 1:50–200; WB: 1:500–1:2000; IHC-p: 1:100–1:300; ELISA: 1:20000. Not yet tested in other applications. |
| Immunogen | Synthesized peptide derived from human EPAS-1 around the non-acetylation site of K385. |
| Host | Rabbit |
| Storage | -20°C, 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 96 kDa |
| Gene ID (Human) | 2034 |
| Human Swiss-Prot No. | Q99814 |
| Cellular Localization | Nucleus; Nucleus speckle; Colocalizes with HIF3A in the nucleus and speckles. |
| Species Reactivity | Human; Mouse; Rat |
Background
Endothelial PAS domain protein 1 (EPAS1) is a transcription factor involved in the induction of genes regulated by oxygen levels. It is activated under hypoxic conditions and contains a basic-helix-loop-helix domain, a protein dimerization domain, and a PAS domain found in proteins involved in oxygen-sensing signal transduction pathways. Mutations in this gene are associated with familial erythrocytosis type 4.
[Provided by RefSeq, Nov 2009]
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