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ELK Biotechnology E2F-4 rabbit pAb
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ELK Biotechnology E2F-4 rabbit pAb

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E2F-4 rabbit pAb는 인간, 마우스, 랫트에서 반응하는 폴리클로날 항체로 세포 주기 조절 관련 E2F4 단백질 검출에 사용됩니다. WB, IHC, IF, ELISA에 적합하며 고순도 IgG 형태로 제공됩니다. -20°C에서 1년간 안정적으로 보관 가능합니다.

판매단위
pk
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ELK Biotechnology ES4052-100UL E2F-4 rabbit pAb, 100UL pk판매 단위 pk ·
재고 확인 필요
402,000원VAT 포함 442,200원
ELK Biotechnology ES4052-50UL E2F-4 rabbit pAb, 50UL pk판매 단위 pk ·
재고 확인 필요
301,000원VAT 포함 331,100원

ELK Biotechnology · ELK Biotechnology E2F-4 rabbit pAb

제품명

E2F-4 rabbit pAb

공급업체

ELK Biotechnology

제품 정보

항목 내용
Alternative Names E2F4; Transcription factor E2F4; E2F-4
Applications WB; IHC; IF; ELISA
Recommended Dilutions Western Blot: 1/500 - 1/2000
IHC-p: 1/100 - 1/300
ELISA: 1/20000
Not yet tested in other applications
Immunogen Synthesized peptide derived from human E2F4 around the non-acetylation site of Lys96 (AA range: 61–110)
Host Rabbit
Storage -20°C / 1 year
Clonality Polyclonal
Isotype IgG
Concentration 1 mg/ml
Observed Band 43 kD
GeneID (Human) 1874
Human Swiss-Prot No Q16254
Cellular Localization Nucleus
Species Reactivity Human; Mouse; Rat

Background

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of the cell cycle and in the action of tumor suppressor proteins, and is also a target of the transforming proteins of small DNA tumor viruses.
E2F proteins contain several evolutionarily conserved domains, including:

  • DNA binding domain
  • Dimerization domain (interacts with DP transcription factors)
  • Transactivation domain enriched in acidic amino acids
  • Tumor suppressor protein association domain (within the transactivation domain)

This protein binds to tumor suppressor proteins pRB, p107, and p130, with higher affinity to p107 and p130. It plays an important role in suppression of proliferation-associated genes.

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