
ELK Biotechnology ERp57 rabbit pAb
ERp57 rabbit pAb는 인간 PDIA3 유래 펩타이드로부터 제작된 폴리클로날 항체로, WB, IHC, IF, ELISA에 적합합니다. ER 내 단백질 접힘과 이황화 결합 형성 연구에 활용되며, 사람·마우스·랫트 시료에 반응합니다. -20°C에서 1년 보관 가능합니다.
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제품명
ERp57 rabbit pAb
공급업체
ELK Biotechnology
제품 개요
ERp57 rabbit pAb는 인간 PDIA3의 내부 영역(AA 111–160)에서 유래한 합성 펩타이드로 면역화된 폴리클로날 항체입니다. 이 항체는 ER 내 단백질 접힘을 조절하는 ERp57 단백질을 검출하는 데 사용됩니다.
제품 스펙
| 항목 | 내용 |
|---|---|
| Product name | ERp57 rabbit pAb |
| Alternative Names | PDIA3; ERP57; ERP60; GRP58; Protein disulfide-isomerase A3; 58 kDa glucose-regulated protein; 58 kDa microsomal protein; p58; Disulfide isomerase ER-60; Endoplasmic reticulum resident protein 57; ER protein 57; ERp57; Endoplasmic reticulum resident protein 60; ER protein 60; ERp60 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | Western Blot: 1/500–1/2000 IHC-p: 1/100–1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the internal region of human PDIA3 (AA range: 111–160) |
| Host | Rabbit |
| Storage | −20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 55 kD |
| Gene ID (Human) | 2923 |
| Human Swiss-Prot No. | P30101 |
| Cellular Localization | Endoplasmic reticulum, endoplasmic reticulum lumen, melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:12643545). |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
[Provided by RefSeq, Jul 2008]
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