
ELK Biotechnology Neuregulin-2 rabbit pAb
Neuregulin-2 rabbit pAb는 인간, 마우스, 랫트 시료에 반응하는 다클론 항체입니다. WB, IHC, IF, ELISA에 적합하며 1mg/ml 농도로 제공됩니다. 세포막 및 분비 단백질 검출에 유용하며, -20°C에서 1년 보관 가능합니다.
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제품명
Neuregulin-2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | NRG2; NTAK; Pro-neuregulin-2, membrane-bound isoform; Pro-NRG2 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | WB: 1/500–1/2000 IHC-p: 1/100–1/300 ELISA: 1/20000 Not yet tested in other applications |
| Immunogen | Synthesized peptide derived from the internal region of human NRG2 (AA range: 361–410) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 90 kDa |
| Gene ID (Human) | 9542 |
| Human Swiss-Prot No. | O14511 |
| Species Reactivity | Human; Mouse; Rat |
| Cellular Localization | [Pro-neuregulin-2, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein (inactive) [Neuregulin-2]: Secreted |
Background
This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and its genomic structure is similar to that of neuregulin 1, another member of the neuregulin family. These genes mediate distinct biological processes by acting at different sites in tissues and eliciting different cellular responses. The gene is located near the demyelinating Charcot-Marie-Tooth disease locus but is not responsible for the disease. Alternative transcript variants encoding distinct isoforms have been described. [RefSeq, May 2010]
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