Thermo Fisher Scientific UCK1 Monoclonal Antibody (OTI6E12), TrueMAB

Applications

• Western Blot (WB): 1:2,000 dilution tested

Product Specifications

Product Specific Information

For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

UCK1 (Uridine-cytidine kinase 1) phosphorylates uridine and cytidine to form uridine monophosphate (UMP) and cytidine monophosphate (CMP).
It does not phosphorylate deoxyribonucleosides or purine ribonucleosides.
Can utilize ATP or GTP as a phosphate donor and also phosphorylates various cytidine and uridine analogs such as:

• 6-azauridine
• 5-fluorouridine
• 4-thiouridine
• 5-bromouridine
• N(4)-acetylcytidine
• N(4)-benzoylcytidine
• 5-fluorocytidine
• 2-thiocytidine
• 5-methylcytidine
• N(4)-anisoylcytidine

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.