Thermo Fisher Scientific CD100 Polyclonal Antibody
인간 CD100(SEMA4D)을 인식하는 Rabbit Polyclonal Antibody로 Western blot에 최적화됨. 항원 친화 크로마토그래피로 정제되어 고순도 확보. 액상 형태, 1 mg/mL 농도, PBS 버퍼 및 0.02% sodium azide 포함. 연구용으로만 사용 가능.
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Thermo Fisher Scientific CD100 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500 dilution
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues K(777) P K S D F C D R E Q S(788) of human CD100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2185712 |
Product Specific Information
PA1-4202 detects CD100 in human samples.
It has been successfully used in Western blot procedures.
By Western blot, this antibody detects a ~158 kDa protein representing CD100 in transfected CHO cells.
The immunogen is a synthetic peptide corresponding to residues K(777) P K S D F C D R E Q S(788) of human CD100.
Target Information
Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development.
CD100 (also known as semaphorin 4D), a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro.
CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and downregulating CD23 expression.
CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling.
CD100 is expressed on resting and PHA-stimulated T cells. The protein is weakly expressed on NK cells, EBV-transformed B cells, monocytes, and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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