
Thermo Fisher Scientific CTLA-4 (CD152) Polyclonal Antibody
CTLA-4(CD152) 폴리클로날 항체로 Mouse와 Rat 반응성. Rabbit IgG 호스트로 제작된 비결합형 항체. Western blot, IHC, ELISA에 사용 가능. 항원 친화 크로마토그래피로 정제된 고순도 제품으로 연구용으로 적합.
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Thermo Fisher Scientific CTLA-4 (CD152) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 0.5–1 µg/mL |
| ELISA | 0.1–0.5 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived mouse CTLA4 recombinant protein (Position: E36–D161) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746206 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
CTLA4 (Cytotoxic T-Lymphocyte Antigen 4) is a CD28-family receptor expressed mainly on CD4+ T cells. It binds the same ligands as CD28 (CD80 and CD86 on B cells and dendritic cells) but with higher affinity. Unlike CD28, which enhances T cell activation, CTLA4 inhibits T cell function. Intracellular CTLA4 is also found in regulatory T cells and may play a role in their suppressive activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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