Thermo Fisher Scientific ARRDC1 Polyclonal Antibody
Rabbit polyclonal antibody targeting human ARRDC1 for research use. Validated for Western blot applications with dilution range 1:500–1:1,000. Unconjugated form, 1 mg/mL concentration. Stored at -20°C and shipped on wet ice.
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Thermo Fisher Scientific ARRDC1 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human ARRD1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2555441 |
Target Information
Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458).
Through an ubiquitination-dependent mechanism, plays a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458).
More generally, plays a role in the extracellular transport of proteins between cells through the release of microvesicles into the extracellular space (PubMed:22315426).
By participating in ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940).
[Source: UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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