Thermo Fisher Scientific FIBB Polyclonal Antibody
Western blot, IHC, ICC/IF에 사용 가능한 Rabbit Polyclonal 항체로, 인간 및 생쥐 FGB 단백질을 검출합니다. 합성 펩타이드 면역원으로 제작되었으며, 액상 형태로 제공됩니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FGB (Accession P02675), corresponding to amino acid residues G386–R436 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2854493 |
Product Specific Information
Antibody detects endogenous levels of total FGB.
Target Information
FIBB is the beta component of fibrinogen, a blood-borne glycoprotein composed of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin, the main component of blood clots. Cleavage products of fibrinogen and fibrin also regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and act as mitogens for several cell types. Mutations in the gene can cause afibrinogenemia, dysfibrinogenemia, hypodysfibrinogenemia, and thrombotic disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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