Thermo Fisher Scientific RSF1 Polyclonal Antibody
RSF1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 최적화된 항체로 인간, 생쥐, 랫트 반응성. 고순도 친화 크로마토그래피 정제, 액상 형태로 제공되며 -20°C 보관. 연구용으로만 사용 가능.
- 카탈로그번호
- PA5102998
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human RSF1 (Accession Q96T23), corresponding to amino acid residues E388–G438 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852370 |
Product Specific Information
Antibody detects endogenous levels of total RSF1.
Target Information
RSF1 is required for assembly of regular nucleosome arrays by the RSF chromatin remodeling complex. Rsf1 facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappaB transcription activation. Rsf1 represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. Rsf1 interacts with SMARCA5/SNF2H to form the RSF complex and also binds the HBV pX/HBx protein, which is required to activate transcription of the viral genome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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