Thermo Fisher Scientific FSHR Polyclonal Antibody
FSHR 단백질을 인식하는 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF 등 다양한 응용에 적합. 인간, 생쥐, 랫트 반응성. 고순도 Affinity Chromatography 정제, 액상 형태, -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific FSHR Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FSHR (Accession P23945), corresponding to amino acid residues H215–M265 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2818357 |
Product Specific Information
Antibody detects endogenous levels of total FSHR.
Target Information
Follicle-Stimulating Hormone Receptor (FSHR) is expressed in ovary, uterus, and testis. ESTs have been isolated from testis libraries.
G-protein Coupled Receptors (GPCRs) form one of the largest families of signaling molecules, with over a thousand predicted members.
All GPCRs share a structural motif of seven membrane-spanning helices and exist in active and inactive forms.
Activation by ligands induces signaling via G-proteins and downstream effectors.
Negative regulation mechanisms of GPCRs are crucial for cellular physiology and pharmacological research.
Notable GPCR-targeted drugs include Zyprexa (Eli Lilly) and Claritin (Schering-Plough), both major products in mental health and allergy treatment markets.
Usage Note
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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