Thermo Fisher Scientific PPAN Polyclonal Antibody
Human PPAN 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC(P) 적용 가능. 항원 친화 크로마토그래피로 정제되었으며, 0.3 mg/mL 농도의 액상 형태. PBS(glycerol 포함) 완충액에 보관하며 4°C 단기, -20°C 장기 보관 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PPAN. Recombinant protein control fragment (Product # RP-99100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2645802 |
Product Specific Information
Immunogen sequence:
RWEMDRGRGR LCDQKFPKTK DKSQGAQARR GPRGASRDGG
Highest antigen sequence identity to orthologs:
- Mouse: 38%
- Rat: 38%
Target Information
The protein encoded by this gene is an evolutionarily conserved protein similar to yeast SSF1 and the Drosophila gene peter pan (ppan). SSF1 is involved in the second step of mRNA splicing, and both SSF1 and ppan are essential for cell growth and proliferation.
Exogenous expression of this gene reduces anchorage-independent growth of some tumor cells.
Read-through transcription with the adjacent downstream gene P2RY11/P2Y(11), encoding an ATP receptor, has been observed. These transcripts are ubiquitously present and up-regulated during granulocyte differentiation.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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