Thermo Fisher Scientific CD38 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0892)
Recombinant alpaca monoclonal antibody targeting human CD38, suitable for ELISA applications. Expressed in CHO cells with 8His-Cys tag, purified by metal-chelate chromatography. Supplied as liquid form in PBS without preservative. For research use only.
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Thermo Fisher Scientific CD38 VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA0892)
Applications
- ELISA (Assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA0892 |
| Immunogen | Recombinant Human CD38/ADPRC 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
CD38 (NAD+ glycohydrolase) is a type II transmembrane glycoprotein that induces activation, proliferation, and differentiation of mature lymphocytes, and mediates apoptosis of myeloid and lymphoid progenitor cells.
It functions as a multi-catalytic ectoenzyme serving as ADP-ribosyl cyclase, cyclic ADP-ribose hydrolase, and possibly NAD+ glycohydrolase, or as a cell surface receptor.
Antibodies to CD38 are useful in subtyping lymphomas and leukemias, detecting plasma cells (e.g., identification of myelomas), and as markers for activated B and T cells.
CD38 participates in cell adhesion, signal transduction, and calcium signaling. It is highly expressed in pancreas, liver, kidney, malignant lymphoma, and neuroblastoma.
Diseases associated with CD38 dysfunction include chronic lymphocytic leukemia and Richter’s Syndrome.
Usage Note
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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