Thermo Fisher Scientific Human BAP3 Synthetic Peptide
인간 BAP3의 아미노 말단 12개 아미노산 서열을 기반으로 한 합성 펩타이드입니다. 항체 PA5-20499와 함께 블로킹 펩타이드로 사용 가능합니다. 뇌에서 주로 발현되는 BAP3 단백질 연구에 적합하며, 암세포 증식 관련 연구에도 활용됩니다.
- 카탈로그번호
- PEP0619
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 12 amino acids near the amino terminus of human BAP3.
PEP-0619 can be used as a blocking peptide with polyclonal antibody PA5-20499.
Target Information
BAP3 was initially identified through interaction in a yeast two-hybrid system with the brain-specific angiogenesis inhibitor 1, a p53-target gene that encodes a seven-span transmembrane protein member of the secretin receptor family.
BAP3 is predominantly expressed in the brain and possesses high homology with Munc13 and synaptotagmin, suggesting that BAP3 may play a role in regulating neurotransmitter release.
Recent experiments have shown that BAP3 is induced in certain tumors such as desmoplastic small round cell tumor. Ectopic expression of BAP3 in tumor cells dramatically enhances growth in low serum conditions and colony formation in soft agar, suggesting that the regulated exocytotic pathway may play a role in cancer cell proliferation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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