
Thermo Fisher Scientific CD4 Monoclonal Antibody (OTI16D11), TrueMAB
Human CD4 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot에 적합합니다. TrueMAB 형식의 고순도 항체이며, 1 mg/mL 농도로 PBS/BSA/glycerol buffer에 보존됩니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
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Applications
- Western Blot (WB)
Tested Dilution: 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI16D11 |
| Immunogen | Full length human recombinant protein of human CD4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and acts as a co-receptor for HIV. CD4 is primarily expressed in T helper cells, but also in monocytes, macrophages, and dendritic cells. Tissue-level expression includes thymus, lymph nodes, tonsils, spleen, and specific regions of the brain and gut. CD4 assists in T-cell activation via association with the T-cell receptor complex and kinase Lck, and may mediate neuronal damage in infectious or immune-mediated CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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