Thermo Fisher Scientific QPRT Monoclonal Antibody (OTI7A8), TrueMAB
QPRT 단백질을 인식하는 mouse monoclonal antibody로, Western blot, IHC, Flow cytometry에 사용 가능. 인간 시료에 반응하며, 동결건조 형태로 제공. PBS buffer에 보관되며 연구용으로 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI7A8 |
| Immunogen | Full length human recombinant protein of human QPRT produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The QPRT gene encodes a key enzyme in the catabolism of quinolinate, an intermediate in the tryptophan–nicotinamide adenine dinucleotide pathway.
Quinolinate acts as a potent endogenous excitotoxin to neurons. Elevated quinolinate levels in the brain are linked to neurodegenerative disorders such as epilepsy, Alzheimer’s disease, and Huntington’s disease.
Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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