Thermo Fisher Scientific SPAG5 Monoclonal Antibody (OTI6G2)
SPAG5 단백질을 인식하는 Thermo Fisher Scientific의 단일클론 항체. Western blot에 최적화되어 있으며, 인간 시료에 반응. 고순도 친화 크로마토그래피로 정제된 액상 항체로, 안정적인 저장용 PBS 버퍼 포함. 연구용 전용 제품.
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6G2 |
| Immunogen | Human recombinant protein fragment (amino acids 1–297 of SPAG5) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723664 |
Target Information
SPAG5 (sperm associated antigen 5), also known as MAP126, hMAP126, DEEPEST or Astrin, is a 1,193 amino acid protein expressed at high levels in testis and lower levels in liver, placenta, pancreas, colon, and thymus. It localizes to spindle poles during prophase and throughout the spindle during metaphase and anaphase, playing an essential role in spindle formation and mitotic regulation. SPAG5 also contributes to sister chromatid cohesion and separation, maintaining chromosome integrity. The protein forms homodimers with a long stalk and globular head domain, creating aster-like structures. Upon DNA damage, SPAG5 may be phosphorylated by ATR or ATM.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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