Thermo Fisher Scientific CYP2E1 Monoclonal Antibody (OTI5F11)
CYP2E1 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC, ICC/IF에 사용 가능. 인간, 마우스, 랫트 반응성. 친화 크로마토그래피로 정제된 액상 항체이며, PBS 버퍼와 글리세롤 함유. 약물 대사 및 간 연구용에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F11 |
| Immunogen | Full length human recombinant protein of CYP2E1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2723039 |
Target Information
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids, and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation.
The enzyme metabolizes both endogenous substrates (e.g., ethanol, acetone, acetal) and exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines found in cigarette smoke. Due to its many substrates, this enzyme may be involved in processes such as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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