Thermo Fisher Scientific FBXO8 Monoclonal Antibody (OTI3C5)
FBXO8 단백질을 표적하는 Thermo Fisher Scientific의 단클론 항체로, Western blot 및 IHC(P) 실험에 적합합니다. 인간 시료 반응성이 있으며, 고순도 친화 크로마토그래피 정제 제품입니다. 연구용으로만 사용됩니다.
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Applications
- Western Blot (WB): 1:2,000
- Immunohistochemistry (Paraffin) (IHC (P)): 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C5 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–231 of FBXO8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724295 |
Target Information
This gene encodes a member of the F-box protein family characterized by an approximately 40 amino acid motif, the F-box. These proteins form part of the SCF (SKP1-cullin-F-box) ubiquitin ligase complex, functioning in phosphorylation-dependent ubiquitination.
F-box proteins are grouped into three classes:
- Fbws – containing WD-40 domains
- Fbls – containing leucine-rich repeats
- Fbxs – containing various protein-protein interaction modules or no recognizable motifs
The FBXO8 protein belongs to the Fbxs class and has a C-terminal sequence similar to yeast Sec7p, a regulator of vesicular protein transport. It may interact with ADP-ribosylation factors (ARFs) and exhibit ARF-GEF activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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