
Thermo Fisher Scientific CYP2B6 Polyclonal Antibody
인간 CYP2B6 단백질을 인식하는 염소 유래 폴리클로날 항체. Western blot에 적합하며 TBS 기반 버퍼에 보관. 약물 대사 관련 연구용으로 사용. -20°C 보관, 동결/해동 반복 피해야 함.
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- pk
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Applications
- Western Blot (WB): 0.1–0.3 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence C-HSVEKHRETLDPS (aa 247–259) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Wet ice |
| RRID | AB_2933884 |
Product Specific Information
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.
Target Information
The CYP2B6 gene encodes a member of the cytochrome P450 enzyme superfamily. These monooxygenases catalyze reactions involved in drug metabolism and the synthesis of cholesterol, steroids, and other lipids.
This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. It metabolizes certain xenobiotics such as the anti-cancer drugs cyclophosphamide and ifosphamide.
Transcript variants have been described, though it remains unclear whether these originate from this gene or a closely related pseudogene, CYP2B7. Both are located within a large cluster of cytochrome P450 genes on chromosome 19q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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